Personalized Immune Mouse to Study Autoimmune Disease
Columbia University Medical Center scientists have developed a new “personalized immune mouse,” a new tool that allows them to re-create an individual’s immune system to study autoimmune diseases.
Immunogenicity and Safety of Quadrivalent Live Attenuated Influenza Vaccine in Children
A randomized, double-blind study was conducted to demonstrate the immunologic noninferiority of an investigational quadrivalent live attenuated influenza vaccine (Q/LAIV) developed by MedImmune.
Intravenous Immunoglobulin Protects Neurons Against Amyloid Beta-Peptide Toxicity: In Vitro and Murine Studies
A multinational team of investigators exposed cultured neurons with intravenous immunoglobulin (IVIG) to evaluate its effect on downstream signaling pathways involved in neuronal cell death.
Smallpox Vaccine Extends Life in Cancer Trial
A genetically engineered smallpox vaccine reduced the risk of death for patients with advanced liver cancer by nearly 60 percent in a mid-stage study.
Slow Release of IG May Delay Alzheimer’s Disease
Recent studies suggest that the divergent outcomes in Alzheimer’s disease clinical studies of intravenous immune globulin (IVIG) may be due to differences in temporal administration and administered dosages.
Positive Results for Phase II Clinical Trial for ITP Patients
A recent study showed that recombinant polyclonal antibody drug candidate rozrolimupab exhibited a favorable safety profile and induced a rapid increase in blood platelets inpatients with immune thrombocytopenia purpura.
Immunization Innovation: Advancements in Science and Policy Show Potential
Through continued breakthroughs in vaccine research and technology, scientists are developing new techniques and approaches to address historical illnesses, and updates in policy aren’t far behind.
Alzheimer’s Research Receives More Funding
The federal government has devoted new funding for Alzheimer’s disease research.
Over Half of U.S. Hemophilia Treatment Centers Do Not Follow NHF Guidelines for Factor VIII Prophylaxis in Severe Hemophilia A
Factor VIII prophylaxis every other day (qod) or three times weekly is recommended by the National Hemophilia Foundation to prevent joint bleeds in children with severe hemophilia A.
Combined IVIG Treatment Effective to Treat Kawasaki Disease
Researchers from Kitasato UniversitySchool of Medicine in Japan found that combining intravenous methylprednisolone pulse and intravenous immunoglobulin to treat patients with Kawasaki disease appears safe and effective.