New Biosimilar Autoimmune Disease Treatment Approved by FDA

Celltrion’s Avtozma (tocilizumab-anoh), a biosimilar to Actemra (tocilizumab), in both intravenous and subcutaneous formulations, has been approved by the U.S. Food and Drug Administration.
FDA Approves New Medication for Acute Pain

The U.S. Food and Drug Administration has approved Vertex Pharmaceutical’s Journavx (suzetrigine), a new type of prescription pain medication for adults to treat moderate to severe acute pain.
Multiple Myeloma Patients Treated with Teclistamab May Benefit from IVIG Supplementation

Results of a recent study show patients with multiple myeloma undergoing teclistamab therapy may benefit from primary intravenous immune globulin supplementation, which appears to reduce the risk of high-grade infection.
Coupling HA Molecules from Various Flu Strains Could Make Vaccines More Effective

Results from a recent study suggest coupling HA molecules from various flu strains could make flu vaccines more effective.
Study Shows IVIG Is Associated with Sepsis Mortality

A study published in Frontiers in Immunology has found the administration of intravenous immune globulin (IVIG) is associated with a reduction in sepsis mortality and favorable outcomes in laboratory parameters and the functional status, contributing to the ongoing debate on the efficacy of IVIG for sepsis.
Blood Test Can Predict How Long Vaccine Immunity Will Last

A study led by researchers at Stanford Medicine has shown that variation in vaccine durability can, in part, be attributed to a type of blood cell called megakaryocytes, typically implicated in blood clotting.
Lab Value Predictive of COVID-19 Disease Severity in Children

A study has found measurements of C-reactive protein (CRP), lactate dehydrogenase (LDH) and albumin are potentially predictive markers for disease severity in children hospitalized with COVID-19. The multi-center retrospective cohort study at four pediatric referral hospitals in Iran between April 2020 and March 2021 assessed the discriminative ability of laboratory and clinical parameters to pinpoint […]
FDA Approves Dupixent for Chronic Obstructive Pulmonary Disease

The U.S. Food and Drug Administration (FDA) has expanded its approval of Dupixent to chronic obstructive pulmonary disease (COPD). This permits Dupixent’s use as an add-on maintenance treatment of adults whose COPD is inadequately controlled by available therapies. The every-other-week injectable drug is now the first biologic therapy approved by FDA for treating COPD, and […]
Changes in Immune Cell Gene Activity May Indicate Probability of Developing MS

Individuals with multiple sclerosis (MS) have high levels of immune cells called cytotoxic T cells, which normally help kill cancer and cells infected by germs. In MS, these cells accumulate in areas with visible myelin damage, but until recent study results, the role the cells play in the disease had remained unknown. In a study […]
HIV Vaccine Elicits Potent Response in Nonhuman Primates

A study conducted by researchers at Weill Cornell Medicine has demonstrated that a series of six vaccinations containing a modified protein from the surface of HIV particles stimulated initial steps of a potent immune response in young nonhuman primates. According to the researchers, this difficult-to-achieve response represents an important step toward providing full and potentially […]