Lab Value Predictive of COVID-19 Disease Severity in Children
A study has found measurements of C-reactive protein (CRP), lactate dehydrogenase (LDH) and albumin are potentially predictive markers for disease severity in children hospitalized with COVID-19. The multi-center retrospective cohort study at four pediatric referral hospitals in Iran between April 2020 and March 2021 assessed the discriminative ability of laboratory and clinical parameters to pinpoint […]
Changes in Immune Cell Gene Activity May Indicate Probability of Developing MS
Individuals with multiple sclerosis (MS) have high levels of immune cells called cytotoxic T cells, which normally help kill cancer and cells infected by germs. In MS, these cells accumulate in areas with visible myelin damage, but until recent study results, the role the cells play in the disease had remained unknown. In a study […]
CSL Begins Enrollment for Hizentra Study for POTS
CSL Ltd. has begun enrolling U.S. patients in a Phase III late-stage randomized control trial to assess whether Hizentra subcutaneous immune globulin (SCIG) can alleviate symptoms of postural orthostatic tachycardia syndrome (POTS) — a blood circulation disorder that is one of the most common and disabling symptoms of long COVID with no approved therapies. The […]
mRNA Cancer Vaccine Begins Trials for Non-Small Cell Lung Cancer
An mRNA vaccine has entered human trials as a treatment for lung cancer. Unlike traditional cancer vaccines such as the HPV vaccine, BNT116 is a therapeutic cancer vaccine designed to reduce tumor growth in patients with cancer or prevent its recurrence. BNT116 contains the genetic code for six molecules frequently seen in non-small cell lung […]
Multi-Million Dollar Grant Awarded for Organ Transplantation Research
Researchers at the Terasaki Institute for Biomedical Innovation have been awarded a multi-million dollar grant from the National Institutes of Health (NIH) to advance research in organ transplantation and antibody mediated rejection. The research will focus on creating a state-of-the-art multi-organs-on-a-chip platform comprised of a vascularized liver-on-a-chip and heart-on-a-chip, with a fully integrated biosensor system […]
In the R&D Pipeline: New Agents to Prevent and Treat Hereditary Angioedema Attacks
TISSUE EDEMA is a normal component of the acute inflammatory response to localized injury caused by invading pathogens, trauma, toxins, heat or other causes. This protective tissue swelling phenomenon is regulated in part by a protease inhibitor called complement 1 esterase inhibitor (C1-INH). But individuals affected with hereditary angioedema (HAE) experience recurrent attacks of localized […]
Scientists Develop $25 Nasal Spray That Is 99% Effective Against Colds, Flu and COVID-19
Scientists at Harvard Medical School have developed a simple nasal spray, made of harmless ingredients, that can protect people against flu, colds and COVID-19 with near-100 percent success, and it costs just $25. The new spray is called the Pathogen Capture and Neutralizing Spray, or PCANS, though they are marketing it under the name Profi. […]
New Type of Blood Test Can Identify Kids at Risk of Diabetes
Scientists at Kings College London have discovered a novel link between lipids and disorders affecting children’s metabolism that may provide an early warning system for obesity-related problems such as type 2 diabetes and liver and heart disease. The researchers say this could assist medical professionals in identifying early disease indicators in children more quickly and […]
Nasal Swab May Predict Severity of COVID-19
New research suggests autoantibodies in the nasal cavity may predict the severity of COVID-19 disease.
CSL Begins Enrollment for Hizentra Study for POTS
CSL Ltd. has begun enrolling U.S. patients in a Phase III late-stage randomized control trial to assess whether Hizentra subcutaneous immune globulin (SCIG) can alleviate symptoms of postural orthostatic tachycardia syndrome (POTS) — a blood circulation disorder that is one of the most common and disabling symptoms of long COVID with no approved therapies.
