Study Finds Immunotherapy Causes Chronic Side Effects
A recent study has found chronic immune-related side effects are common in patients with skin cancer who are treated with postsurgical Opdivo (nivolumab) or Keytruda (pembrolizumab), although for some individuals, these toxicities resolve by the 18-month mark.
IVIG May Improve Neurological Symptoms in MIS-C
Recent case series findings, as well as previous studies, show that children with multisystem inflammatory syndrome (MIS-C) who present with signs of active neurological symptoms may show improvement with intravenous immune globulin (IVIG) and corticosteroids.
Digital Therapeutics: The Next Frontier
This growing field of intervention-based therapeutics promises to enhance patient health and make healthcare more proactive.
Albumin Administration Linked to Lower Risk of Hyponatremia in Hospitalized Cirrhosis Patients: Single-Center Study
Short-term human albumin infusion significantly reduced the incidence of hyponatremia and increased the rate of improvement of hyponatremia in hospitalization hepatic cirrhosis patients.
High-Dose IVIG Reduces Mortality Risk in Hospitalized Patients with Severe COVID-19: Systematic Review and Meta-Analysis
A systematic search of leading databases and registries by Chinese collaborators compared the efficacy of IVIG to routine care for hospitalized COVID-19 patients.
Experimental mRNA Vaccine Plus Keytruda Delays Melanoma Recurrence
A new study shows that a personalized messenger RNA (mRNA) cancer vaccine plus the checkpoint inhibitor Keytruda (pembrolizumab) reduced the risk of recurrence or death in people with high-risk advanced melanoma.
New Approach May Better Treat SLE
Findings in a recent study suggest that targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus.
Study Links Persistent Tumor Mutation with Therapeutic Response to Immunotherapy Schedule
Investigators have found that a subset of mutations within the overall tumor mutation burden are less likely to be edited out as cancer evolves.
Post-AMI Infusion of Human Apolipoprotein A-1 (CSL112) Strongly Boosts Impaired Cholesterol Efflux Capacity
Infusion of CSL112, an investigational human plasma-derived apolipoprotein A-1 formulated with phosphatidylcholine, rapidly and strongly elevates impaired cholesterol efflux capacity following acute myocardial infarction.
IVIG May Improve Survival in Patients with Acute Exacerbation of Fibrotic Idiopathic Interstitial Pneumonia
Investigators have found that intravenous immune globulin may have a positive effect on acute exacerbation of fibrotic idiopathic interstitial pneumonias.