Experimental mRNA Vaccine Plus Keytruda Delays Melanoma Recurrence
A new study shows that a personalized messenger RNA (mRNA) cancer vaccine plus the checkpoint inhibitor Keytruda (pembrolizumab) reduced the risk of recurrence or death in people with high-risk advanced melanoma.
FDA Retires Monovalent COVID-19 Vaccines
The U.S. Food and Drug Administration has amended the emergency use authorizations of the. Moderna and Pfizer-BioNTech COVID-19 bivalent mRNA vaccines to simplify the vaccination schedule for most individuals.
Study Finds Experimental Alzheimer’s Drug Slows Cognitive Decline
A large clinical trial of Eli Lilly’s experimental Alzheimer’s medication, donanemab found the drug slowed declines in patients’ ability to think clearly and perform daily tasks by more than a third.
Pfizer’s LITFULO for Severe Alopecia Areata Approved by FDA
The U.S. Food and Drug Administration has approved LITFULO (ritlecitinib), a once-daily oral treatment, for individuals 12 years of age and older with severe alopecia areata.
First Subcutaneous Injectable Approved to Treat Generalized Myasthenia Gravis
The subcutaneous formulation of argenx’s Vyvgart has been approved by the U.S. Food and Drug Administration to treat generalized myasthenia gravis.
FDA Approves Roche’s Columvi to Treat Diffuse Large B-Cell Lymphoma in Adults
The U.S. Food and Drug Administration has approved Roche’s Columvi, an antibody-based therapy chemically known as glofitamab.
mRNA-Based Vaccine Plus Keytruda Reduces the Risk of Melanoma Spread
Adding an experimental mRNA-based vaccine developed by Moderna and Merck & Co to Keytruda reduced the risk that melanoma would spread by 65 percent over treatment with the immunotherapy drug alone, according to a midstage trial.
Drug Granted Fast Track Approval to Treat Refractory Lupus Nephritis
The US Food and Drug Administration has granted fast track designation for Kyverna Therapeutics’ KYV-101 to treat refractory lupus nephritis.
Study Finds Meningitis Vaccine Shows Promise
According to a new study, a meningitis vaccine tested in two African countries has shown promise in the fight against the disease, eliciting immune responses against five main strains. The Phase III randomized trials were conducted on 1,800 people in the West African nations of Mali and The Gambia. The under-trial NmCV-5 vaccine, developed by […]
New Approach May Better Treat SLE
Findings in a recent study suggest that targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus.