CSL Behring Will Discontinue Carimune NF in Third Quarter 2018
Discontinuation of the product is due to the preference among healthcare professionals and patients for newer, more advanced immune globulin options.
Plasma Exchange with 5% Albumin Associated with Marked Stabilization of Brain Perfusion in Alzheimer’s
Plasma exchange with 5% albumin replacement was associated with marked stabilization of brain perfusion in patients with mild to moderate Alzheimer’s disease during a 21-week treatment period and reduced perfusion loss compared to control subjects at six-month follow up, according to findings from a sham-controlled Phase II clinical trial.
Expanding Uses of IVIG
Researchers are taking a closer look at intravenous immune globulin for its potential to stop the progression of multiple complex conditions from lupus to multiple sclerosis.
Plasma-Derived Apolipoprotein A-I Infusions Are Well-Tolerated, Acutely Increase Cholesterol Efflux Capacity
Human and recombinant apolipoprotein A-I (apoA-I) is the primary functional component of high-density lipoprotein, and has been shown to increase cholesterol efflux capacity and to regress atherosclerotic disease in animal and clinical studies.
Study Finds Blood Plasma Can Restore Brain Function
Results from a new study show that brain function can be restored by human blood plasma.
Reduced Mortality with Use of Four-Factor Prothrombin Complex Concentrates vs. FFP for Warfarin Reversal: Meta-Analysis
The optimal reversal strategy for urgent reversal of warfarin is unclear, but Canadian investigators conducted a systematic review of the clinical literature through December 2015, and identified five randomized clinical trials and eight observational studies for evaluation.
Topical Use of Fibrin Sealant Can Reduce Blood Loss and Need for Transfusion in Total Knee and Hip Arthroplasty
To assess the safety and effectiveness of topical administration of fibrin sealants on postoperative blood loss and blood requirements in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA), Chinese investigators searched electronic medical databases through February 2016 to identify randomized clinical trials (RCTs) for inclusion in a meta-analysis.
Recombinant Human Prothrombin Prevents Bleeding in Hemophilia A and B Mice
Both a plasma-derived human factor II (pdhFII) and an investigational recombinant human prothrombin (MEDI8111) dose-dependently decreased blood loss and bleeding time in hemophilia A mice, according to Swedish investigators at AstraZeneca’s CVMD IMED unit.
Blood Protein Therapeutics: It All Starts with the Plasma
The plasma donor is the first vital part of the process to produce safe and effective plasma protein therapeutics, and the industry prioritizes the safety and health of its plasma donors.
Plasma Exchange Effective in a Subset of Patients with Complex Regional Pain Syndrome
Usually developing following trauma, complex regional pain syndrome (CRPS) has been postulated to be associated with distal degeneration of small-diameter peripheral axons.