Site Advocacy Group Initiative Launched for Clinical Research
The Society for Clinical Research Sites (SCRS) and TransCelerate BioPharma Inc. have launched the Site Advocacy Group (SAG), an initiative that enables clinical investigators and site professionals to interact directly with senior industry leaders in the exchange of perspectives and experiences on innovative ideas, processes, tools and technologies.
High-Dose IVIG Associated with Improved Recovery of Left Ventrical Function in Acute Myocarditis and/or Early DCM
To evaluate the effect of intravenous immune globulin (IVIG) on cardiac rhythm and function in children younger than 12 years of age presenting with acute myocarditis and/or early dilated cardiomyopathy (DCM), investigators at a tertiary hospital in India conducted a retrospective analysis of case records between January 2010 and December 2012.
Albumin Versus Crystalloids in ARDS
Experimental and clinical data show that, compared with crystalloids, colloid fluid therapy mediates multiple beneficial effects in the lungs of patients suffering from acute respiratory distress
syndrome (ARDS), including reduced alveolar-capillary permeability, reduced histological damage, reduced inflammatory cell infiltration and faster hemodynamic stabilization.
Blood Test Could Predict Death Risk
Researchers in Finland and Estonia have discovered novel biological markers that are strongly indicative of the risk of dying from any disease within the next five years.
Facilitators Identified in Uptake of Flu Vaccine by Healthcare Personnel
Researchers recently conducted a quality improvement project to increase uptake of the influenza vaccine among healthcare personnel at a university student health center.
Four-Factor Prothrombin Complex Concentrate Superior to Plasma for Warfarin Reversal Required Prior to Urgent Surgery
In April 2013, the first nonactivated four-factor prothrombin complex concentrate (4F-PCC; Kcentra, CSL Behring) was approved for urgentVKA reversal in patients with acute major bleeding.
IVIG May Improve Left Ventrical Function and Reduce Episodes of Arrhythmia in Adults with Acute Fulminant Myocarditis
Chinese investigators conducted an observational retrospective case study of inpatients presenting at Guangdong General Hospital with acute fulminant myocarditis (AFM) between January 2001 and December 2010.
Intravenous Immunoglobulin (Privigen) Effective, Well-Tolerated as Therapy for Chronic Inflammatory Demyelinating Polyneuropathy
In a prospective, multicenter, single-arm, open-label PhaseIII study, 61 percent of patients with chronic inflammatory demyelinating polyneuropathy (CIDP) responded to induction and maintenance therapy with a 10% liquid human intravenous immunoglobulin (IVIG) (Privigen, CSL Behring).
Study Reveals Barriers to Flu Vaccine for Pregnant Women
A recent study conducted to evaluate barriers to pregnant women’s uptake of the influenza vaccine found that the decline in vaccination among this population was due to lower levels of knowledge and unfavorable attitudes regarding the vaccine’s safety and efficacy.
Immunogenicity, Reactogenicity and Safety of Quadrivalent and Trivalent Influenza Vaccines
A total of 4,659 adults aged 18 years or older were randomized to receive a single dose of inactivated quadrivalent influenza vaccine (IIV4) from one of three production lots or an inactivated trivalent influenza vaccine (IIV3) containing either a B/Victoria or B/Yamagata strain.
