Changes in Immune Cell Gene Activity May Indicate Probability of Developing MS
Individuals with multiple sclerosis (MS) have high levels of immune cells called cytotoxic T cells, which normally help kill cancer and cells infected by germs. In MS, these cells accumulate in areas with visible myelin damage, but until recent study results, the role the cells play in the disease had remained unknown. In a study […]
mRNA Cancer Vaccine Begins Trials for Non-Small Cell Lung Cancer
An mRNA vaccine has entered human trials as a treatment for lung cancer. Unlike traditional cancer vaccines such as the HPV vaccine, BNT116 is a therapeutic cancer vaccine designed to reduce tumor growth in patients with cancer or prevent its recurrence. BNT116 contains the genetic code for six molecules frequently seen in non-small cell lung cancers, which make up 80 to 85 percent of lung cancer diagnoses. Exposure to these six molecules primes immune cells to recognize these molecules on cancer cells and eliminate them.
Multi-Million Dollar Grant Awarded for Organ Transplantation Research
Researchers at the Terasaki Institute for Biomedical Innovation have been awarded a multi-million dollar grant from the NIH to advance research in organ transplantation and antibody mediated rejection.
In the R&D Pipeline: New Agents to Prevent and Treat Hereditary Angioedema Attacks
A number of promising new agents in the R&D pipeline are likely to be approved in the very near future, expanding an already impressive range of treatment options — while further increasing the complexity of the HAE management decision process.
New Type of Blood Test Can Identify Kids at Risk of Diabetes
Scientists at Kings College London have discovered a novel link between lipids and disorders affecting children’s metabolism that may provide an early warning system for obesity-related problems such as type 2 diabetes and liver and heart disease. The researchers say this could assist medical professionals in identifying early disease indicators in children more quickly and […]
New Drug Approved for Children with Severe Immune Disease
Remestemcel-L, a new treatment for children ages 2 months and older with steroid-refractory acute graft-versus-host disease, has been approved by the U.S. Food and Drug Administration.
New Blood Test for Cancer Patients Makes Treatment Safer and More Effective
Scientists from RMIT University and the Doherty Institute in Australia have developed a new blood test that could screen cancer patients to help make their treatment safer and more effective.
Nasal Swab May Predict Severity of COVID-19
New research suggests autoantibodies in the nasal cavity may predict the severity of COVID-19 disease.
CSL Begins Enrollment for Hizentra Study for POTS
CSL Ltd. has begun enrolling U.S. patients in a Phase III late-stage randomized control trial to assess whether Hizentra subcutaneous immune globulin (SCIG) can alleviate symptoms of postural orthostatic tachycardia syndrome (POTS) — a blood circulation disorder that is one of the most common and disabling symptoms of long COVID with no approved therapies.
mRNA Cancer Therapy Boosts Immune Response
An investigational, individualized neoantigen therapy, with personalized encoded mRNA, has demonstrated potential to enable patients’ immune systems to target cells that cause cancer.
