Top-Line Results for Phase III Study of HyQ in PIDD Patients

A Phase III study of HyQ, an investigational facilitated subcutaneous immuneglobulin product for use inpatients with primary immunodeficiency, has produced top-line results.

Urine Test Could Warn About Cognitive Decline

The presence of albuminuria — too much albumin, or protein, in urine — detected by a urine test could be used as an independent predictor of cognitive decline.

Study Tests an Adjuvant to Vaccinate Newborns

A new approach developed that uses an adjuvant along with a vaccine shows that newborns may be able to be vaccinated and protected from disease.

IVIG May Confer Relief in Specific Types of Neuropathy Associated with Sjögren’s Syndrome

A retrospective analysis showed high-dose intravenous immunoglobulin may provide symptomatic relief in patients with sensorimotor neuropathy or nonataxic sensory neuropathy associated with primary Sjögren’s syndrome.

Secondary Prophylaxis with Factor VIII/VWF Concentrate Sharply Reduces Bleeding in Patients with von Willebrand Disease

Long-term prophylactic administration of Octapharma’s Wilate factor VIII/von Willebrand factor(VWF) concentrate dramatically reduced bleeding episodes in 24 patients with von Willebrand disease.

Test Can Predict Immune Responses to Flu Shots

Researchers at the Emory Vaccine Center at Emory University, Atlanta, Ga., have developed a method for predicting whether someone will produce high levels of antibodies against a flu shot a few days after vaccination.

Two Full Doses of Influenza Vaccine Improves Immunogenicity Versus Two Half-Doses in Infants

To assess whether two full doses of trivalent inactivated influenza vaccine could improve immunogenicity versus two halfdoses without increasing reactogenicity in infants (aged 6 to 11months) and toddlers (aged 12 to 23 months), Canadian researchers randomized previously unimmunized children to receive one or the other regimen of 2008-2009 split TIV.

Lower Cholesterol May Fight Infections

Researchers at the University ofEdinburgh have found a direct link between the workings of the immune system and cholesterol levels.

Type of Factor VIII Replacement Product Does Not Affect Inhibitor Risk in Previously Untreated Hemophilia A Patients

Italian investigators performed a systematic review and metaanalysis of published trials to evaluate new inhibitor rates in previously untreated patients (PUPs) with severe hemophilia A.

Protein Identified in Embryo and Disease Development

In a mouse model, researchers discovered that the protein FADD regulated two types of cell deaths pivotal for embryo and disease development.