Moderna’s Flu Vaccine Shows Positive Late-Stage Trial Results

photo of a vaccine syringe

Moderna’s experimental mRNA-based influenze (flu) vaccine produced a stronger immune response than a currently available vaccine in a late-stage trial, clearing a path forward for the product and the company’s separate combination flu and COVID vaccine.

Can Inverse Vaccines Cure Autoimmunity?

BioSupply Trends Quarterly Summer 2025 Inverse Vaccines

While traditional vaccines teach the immune system to fight off foreign invaders, inverse vaccines teach the immune system to ignore its own cells — and may completely reverse autoimmune disease.

Avian Flu and Human Vaccines: Where Things Stand

chickens being tested for avian flu

Shortages and recent spikes in egg prices have boosted public awareness that a “bird flu” is devastating domestic poultry flocks across the country. Since its arrival in the U.S. in January 2022, more than 166 million farmed poultry animals have been sacrificed in an attempt to control the spread of H5N1, a highly pathogenic avian influenza A (HPAI) featuring H5 hemagglutinin and N1 neuraminidase surface proteins (H5N1).

Vaccine Advisers Recommend New RSV Vaccine for Infants

A group of outside advisers to the Centers for Disease Control and Prevention (CDC) voted 5-2 to recommend the use of Merck’s new antibody vaccine, Enflonsia (clesrovimab), that can protect babies from respiratory syncytial virus (RSV).

Novavax’s COVID-19 Vaccine Approved for Older Adults and At-Risk Individuals

After a six-week delay, the U.S. Food and Drug Administration approved Novavax’s COVID-19 vaccine, but only for people 65 and older and those 12 years and older who have at least one underlying condition, such as asthma, diabetes, lung disease, obesity and pregnancy, that puts them at higher risk of severe illness.

Combination Flu and COVID-19 Vaccine Prompts Immune Response in Older Adults

A recent study of Moderna’s combination influenze (flu) and COVID-18 vaccine, mRNA-1083, found that it induced higher immune responses than recommended standard care influenza (standard and high dose) and COVID-19 vaccines against all four influenza strains (among those ages 50 to 64 years), the three clinically relevant influenza strains (among those aged 65 years and older), and SARS-CoV-2 (all ages), with an acceptable tolerability and safety profile.