FDA Grants Full Approval for Spikevax in Children at Increased Risk of Disease

The U.S. Food and Drug Administration (FDA) has granted full approval for Moderna’s Spikevax (mRNA-1273) COVID vaccine in children 6 months through 11 years who are at an increased risk of the disease.

Personalized Melanoma Vaccine Elicits Strong Immune Response

Results of a Dana-Farber Cancer Institute-initiated Phase I clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine called NeoVaxMI is safe, feasible and improves the vaccine-specific immune response compared to previous trials of the platform.

Advances in Vaccine Technology Continue to Save Lives

Despite growing vaccine skepticism, vaccination continues to be a highly effective public health intervention, saving an estimated four to five million lives per year.

HHS and NIH Invest in Universal Vaccine Platform for Pandemic-Prone Viruses

The U.S. Department of Health and Human Services (HHS) and the National Institutes of Health (NIH) have announced the development of the next-generation, universal vaccine platform, Generation Gold Standard, using a beta-propiolactone (BPL)-inactivated, whole-virus platform.

Moderna’s Flu Vaccine Shows Positive Late-Stage Trial Results

Moderna’s experimental mRNA-based influenze (flu) vaccine produced a stronger immune response than a currently available vaccine in a late-stage trial, clearing a path forward for the product and the company’s separate combination flu and COVID vaccine.

Vaccine Safety Dominates Office Visit Concerns

Primary care physicians need considerable help winning the vaccine war given the limited amount of time they have to make their case in the exam room, according to the authors of a new study published online April 15 in the American Journal of Preventive Medicine.

Can Inverse Vaccines Cure Autoimmunity?

While traditional vaccines teach the immune system to fight off foreign invaders, inverse vaccines teach the immune system to ignore its own cells — and may completely reverse autoimmune disease.

Avian Flu and Human Vaccines: Where Things Stand

Shortages and recent spikes in egg prices have boosted public awareness that a “bird flu” is devastating domestic poultry flocks across the country. Since its arrival in the U.S. in January 2022, more than 166 million farmed poultry animals have been sacrificed in an attempt to control the spread of H5N1, a highly pathogenic avian influenza A (HPAI) featuring H5 hemagglutinin and N1 neuraminidase surface proteins (H5N1).

STIs: New Vaccines and Expanding Recommendations

The incidence and prevalence of STIs remain high, and the serious health consequences of contracting one make prevention a national imperative.

Travel Vaccines: What’s Needed and Why?

Protecting Americans against severe disease significantly reduces their chances of getting seriously sick while traveling abroad.