TIL Therapy Found More Effective for Metastatic Melanoma Than Current Treatments
A Phase III clinical trial has found tumor-infiltrating lymphocyte therapy, a new treatment for advanced melanoma, was more effective than ipilimumab, the lading existing therapy.
Researchers Develop a New mRNA Vaccine to Treat Cancer
U.S. researchers have developed a new mRNA vaccine against cancer that delivers the drug directly to the lymphatic system and simulates a strong immune response.
Study Finds Pfizer’s RSV Vaccine Effective in Preventing Illness in Older Adults
Results of a recent study shows Pfizer’s experimental vaccine for respiratory syncytial virus is nearly 86 percent effective in preventing severe illness in older adults.
Experimental RSV Vaccine Shows Promise in Mice
An experimental vaccine shows promise for protecting mice from the respiratory syncytial virus, the pathogen that most commonly causes the chest infection bronchiolitis in young children.
WHO Publishes First Guidelines for Treating Ebola
The World Health Organization has published its first guideline for Ebola virus disease therapeutics, with new strong recommendations for the use of two monoclonal antibodies.
RNA Interference Therapeutic Reduces Hepatotoxic Mutant Z-AAT Levels in Patients with Alpha1-Antitrypsin Deficiency
In a Phase II trial of participants with hepatic disease associated with congenital alpha1-antitrypsin deficiency, subcutaneous administration of fazirsitran, an investigational RNA interference therapeutic, reduced both serum and hepatic levels of the mutant hepatotoxic AAT protein Z-AAT, with concurrent improvements in enzymatic and histological markers of liver function.
Antibody Targeting Tissue Factor Pathway Inhibitor (TFPI) Sharply Reduces Bleeding Rate in Hemophilia A and B Patients
Subcutaneous administration of marstacimab, an investigational human monoclonal antibody targeting tissue factor pathway inhibitor, resulted in a roughly 10-fold lower annualized bleeding rate in 26 hemophilia patients than comparable control individuals in previous clinical trials who were treated on-demand with recombinant factor replacement therapy.
Myths & Facts: COVID-19
While the COVID-19 pandemic is “officially over,” hospitalizations and deaths continue, many of which are due to the myths continuing to circulate about this deadly virus.
The Burden of Lyme Disease
Research into effective treatments for this complicated disease is elusive — and necessary.
Addressing the Mental Health Crisis in Children
The pandemic made a troubling mental health trend in children much worse. What’s being done to help them?
