Personalized Melanoma Vaccine Elicits Strong Immune Response
Results of a Dana-Farber Cancer Institute-initiated Phase I clinical trial for patients with melanoma show that an updated formula and delivery of the NeoVax personalized cancer vaccine called NeoVaxMI is safe, feasible and improves the vaccine-specific immune response compared to previous trials of the platform.
University of Toledo Awarded Funds to Explore Immune Response to Oral Thrush
The University of Toledo will receive $473,632 from the National Institute of Dental and Craniofacial Research to explore how the body’s immune system responds to the condition known as oral thrush.
Activating B Cells Key to TIL Cancer Therapy Effectiveness
Researchers at Moffitt Cancer Center have found that tapping into the body’s own immune system and activating a type of immune cell known as B cells could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy.
Nasal Spray Blocks Infuenza in Mice
Scientists at Ohio State University have created an antibody that was successful in protecting a majority of the tested mice from lethal influenza (flu) doses, even preventing some from experiencing any symptoms at all.
New Antibiotic Enters Phase III Trials to Fight Superburg
Roche’s novel antibiotic zosurabalpin is entering Phase III testing to determine its effectiveness in protecting against carbapenem-resistant Acinetobacter baumannii (CRAB), am antimicrobial resistance (AMR) drug, or “superbug,” that is considered an “urgent threat” by the Centers for Disease Control and Prevention (CDC).
Grifols Receives $21M to Study Parkinson’s Plasma Samples
Grifols has received $21 million from the Michael J. Fox Foundation to fund a pilot study analyzing the company’s repository of longitudinal Parkinson’s disease (PD) plasma samples in hopes of developing an early-warning system for the emergence of PD.
Common Virus May Cause a Type of Alzheimer’s
Researchers have discovered a link between a chronic gut infection caused by cytomegalovirus and the development of Alzheimer’s disease in some people.
Grant Allows UCLA to Launch Autoimmunity Center to Find Cures
The National Institutes of Health has awarded a $3.4 million grant to help establish a new Autoimmunity Center of Excellence at the University of California, Los Angeles.
Adicet Bio’s CAR T-Cell Therapy for SLE Granted Fast Track Designation
The U.S. Food and Drug Administration has awarded fast track designation to Adicet Bio’s novel allogeneic gamma delta CAR-T-cell therapy ADI-001 for adults with refractory systemic lupus erythematosus with extrarenal involvement.
Lab Value Predictive of COVID-19 Disease Severity in Children
A study has found measurements of C-reactive protein (CRP), lactate dehydrogenase (LDH) and albumin are potentially predictive markers for disease severity in children hospitalized with COVID-19. The multi-center retrospective cohort study at four pediatric referral hospitals in Iran between April 2020 and March 2021 assessed the discriminative ability of laboratory and clinical parameters to pinpoint […]
