Immune Disorders Genetic Missing Link Found

An international team of researchers has identified a gene that may be a missing link between overactive and underactive immune activity, and that may also play a key role in autoimmune diseases.

Higher Dosages of 25% Albumin Associated with Lower Incidence of Cerebral Ischemia and Infarction in Pilot ALISAH Study

The “Albumin in Subarachnoid Hemorrhage” (ALISAH) pilot clinical trial, conducted at the Baylor College of Medicine in Houston, assessed the neuroprotective effects of varying dosages of 25% human albumin. Vasospasm, delayed cerebral ischemia (DCI) and cerebral infarction were evaluated in 20 patients who received seven consecutive daily infusions of 0.625 g/kg (Tier 1), 20 who received 1.25 g/kg (Tier 2), and seven who received 1.875 g/kg (Tier 3).

Study Finds Vaccine Side Effects Extremely Rare

An analysis of 67 research studies published in the July 1 edition of Pediatrics has found that serious complications related to vaccines are very rare, and there is no evidence that immunizations cause autism.

Site Advocacy Group Initiative Launched for Clinical Research

The Society for Clinical Research Sites (SCRS) and TransCelerate BioPharma Inc. have launched the Site Advocacy Group (SAG), an initiative that enables clinical investigators and site professionals to interact directly with senior industry leaders in the exchange of perspectives and experiences on innovative ideas, processes, tools and technologies.

Albumin Versus Crystalloids in ARDS

albumin

Experimental and clinical data show that, compared with crystalloids, colloid fluid therapy mediates multiple beneficial effects in the lungs of patients suffering from acute respiratory distress
syndrome (ARDS), including reduced alveolar-capillary permeability, reduced histological damage, reduced inflammatory cell infiltration and faster hemodynamic stabilization.