Study Shows Not All IVIG Products Are Effective in Treating Alzheimer’s
A recent study has found that one specific intravenous immune globulin (IVIG) product was more effective than others in counteracting the cognitive deficits, ameliorating b-amyloid (Ab) deposits and tau phosphorylation among mice with Alzheimer disease (AD)
Scientists Identify Driver of Inflammatory Bowel Disease
Researchers at UT Southwestern Medical Center have discovered an intracellular mechanism that converts protective intestinal cells into disease-driving pathogenic cells, a finding that could lead to improved treatments for patients with inflammatory bowel disease.
Personalized Digital Care Program Improves Outcomes in Long COVID and Autoimmune Disease
According to data, patients with autoimmune diseases or long COVID who used a personalized digital care program (DCP) developed by Mymee alongside other nonpharmacologic strategies were more likely to achieve better health-related quality of life scores.
Researchers Discover How Melanoma Evades the Immune System
Researchers from Sanford Burnham have found that a protein known to be active in immune cells is also active inside melanoma cells, helping promote tumor growth, suggesting that targeting this protein with new drugs may deliver a powerful double hit to melanoma tumors.
FcRn Antagonists: A Panoply of Autoimmune Disorders Now in the Development Pipeline
Specifically designed to blockade the physiologic IgG recycling function of endothelial cell neonatal crystallizable fragment receptor (FcRn), FcRn antagonists represent a new class of monoclonal antibody-based drugs that have been shown to mediate a sharp, dose-dependent reduction in circulation IgG levels.
mRNA-Based Vaccine Plus Keytruda Reduces the Risk of Melanoma Spread
Adding an experimental mRNA-based vaccine developed by Moderna and Merck & Co to Keytruda reduced the risk that melanoma would spread by 65 percent over treatment with the immunotherapy drug alone, according to a midstage trial.
Study Finds Meningitis Vaccine Shows Promise
According to a new study, a meningitis vaccine tested in two African countries has shown promise in the fight against the disease, eliciting immune responses against five main strains. The Phase III randomized trials were conducted on 1,800 people in the West African nations of Mali and The Gambia. The under-trial NmCV-5 vaccine, developed by […]
Message for At-Risk Adults: Flu Vaccination Will Reduce Your Risk of Cardiovascular Disease and Death
With influenza apparently returning with a vengeance this season, the Centers for Disease Control and Prevention is once again alerting the public that vaccination is the most effective way to prevent infection from and to minimize risk of severe symptoms and hospitalization for serious flu-related complications.
High-Dose IVIG Effective in Painful Diabetic Polyneuropathy Resistant to Conventional Treatments
Italian investigators conducted a trial to assess the safety and efficacy of IVIG in treatment-resistant painful diabetic polyneuropathy (DPN).
COVID-19 Infection Alters Pregnant Mothers’ and Their Newborns’ Immunity
Investigators found COVID-19 infection altered the mothers’ immunity at delivery, and gestational COVID-19 exposure alters the immunity of newborns.