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Therapeutics Articles
A study led by scientists at Oregon Health & Science University has found that a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis (ALS).
A recent study has found chronic immune-related side effects are common in patients with skin cancer who are treated with postsurgical Opdivo (nivolumab) or Keytruda (pembrolizumab), although for some individuals, these toxicities resolve by the 18-month mark.
Recent case series findings, as well as previous studies, show that children with multisystem inflammatory syndrome (MIS-C) who present with signs of active neurological symptoms may show improvement with intravenous immune globulin (IVIG) and corticosteroids.
Short-term human albumin infusion significantly reduced the incidence of hyponatremia and increased the rate of improvement of hyponatremia in hospitalization hepatic cirrhosis patients.
A systematic search of leading databases and registries by Chinese collaborators compared the efficacy of IVIG to routine care for hospitalized COVID-19 patients.
A new study shows that a personalized messenger RNA (mRNA) cancer vaccine plus the checkpoint inhibitor Keytruda (pembrolizumab) reduced the risk of recurrence or death in people with high-risk advanced melanoma.
Findings in a recent study suggest that targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus.
Investigators have found that a subset of mutations within the overall tumor mutation burden are less likely to be edited out as cancer evolves.
Infusion of CSL112, an investigational human plasma-derived apolipoprotein A-1 formulated with phosphatidylcholine, rapidly and strongly elevates impaired cholesterol efflux capacity following acute myocardial infarction.
Investigators have found that intravenous immune globulin may have a positive effect on acute exacerbation of fibrotic idiopathic interstitial pneumonias.
Sanofi's fitusiran significantly reduced bleeding in a Phase III multinational study in adults and adolescents with hemophilia A or B, with or without inhibitors.
Italian investigators conducted a trial to assess the safety and efficacy of IVIG in treatment-resistant painful diabetic polyneuropathy (DPN).